Estrogen Patch

The estradiol patch is a transdermal system that releases controlled amounts of estradiol over time. It is commonly prescribed for:

• Menopausal Symptoms: Treating hot flashes, night sweats, vaginal dryness, and mood swings associated with menopaus
• Postmenopausal Bone Health: Reducing the risk of osteoporosis.
• Transgender HRT: As part of feminizing hormone therapy for transgender women.
• Hypoestrogenism: Conditions like ovarian insufficiency or post-hysterectomy.

• Steady Hormone Levels:Provides a consistent release of estradiol, avoiding spikes and dips associated with oral estrogen.
• Reduced Risk of Liver Strain: Transdermal administration bypasses the liver, reducing risks such as increased clotting factors and liver enzyme elevation.
• Customizable Doses: Patches come in various strengths (e.g., 0.025 mg/day, 0.05 mg/day, 0.1 mg/day), allowing dose adjustments.
• Convenience:Applied 1-2 times per week, depending on the brand, making it more convenient than daily pills or injections.

While the estradiol patch is generally well-tolerated, some individuals may experience:

• Skin irritation at the application site.
• Breast tenderness or swelling.
• Nausea or bloating.
• Headaches or mood changes.
• Increased risk of blood clots or stroke (rare, but more common in smokers or those with pre-existing risk factors).

Application Site:

• Place the patch on clean, dry, and non-irritated skin (lower abdomen or buttocks, avoiding breasts).
• Rotate application sites to reduce skin irritation.

Timing: Follow your doctor’s instructions on how often to change the patch.

Avoid Water Interference: The patch is generally water-resistant, but prolonged exposure (like in a hot tub) may loosen it.

Who Should Not Use the Patch?

• People with a history of hormone-sensitive cancers (e.g., breast or uterine cancer), blood clots, stroke, or liver disease.
• Smokers over the age of 35 (due to increased clot risk).