The estradiol patch is a transdermal system that releases controlled amounts of estradiol over time. It is commonly prescribed for:
- Menopausal Symptoms: Treating hot flashes, night sweats, vaginal dryness, and mood swings associated with menopaus
- Postmenopausal Bone Health: Reducing the risk of osteoporosis.
- Transgender HRT: As part of feminizing hormone therapy for transgender women.
- Hypoestrogenism: Conditions like ovarian insufficiency or post-hysterectomy.
- Steady Hormone Levels:Provides a consistent release of estradiol, avoiding spikes and dips associated with oral estrogen.
- Reduced Risk of Liver Strain: Transdermal administration bypasses the liver, reducing risks such as increased clotting factors and liver enzyme elevation.
- Customizable Doses: Patches come in various strengths (e.g., 0.025 mg/day, 0.05 mg/day, 0.1 mg/day), allowing dose adjustments.
- Convenience:Applied 1-2 times per week, depending on the brand, making it more convenient than daily pills or injections.
While the estradiol patch is generally well-tolerated, some individuals may experience:
- Skin irritation at the application site.
- Breast tenderness or swelling.
- Nausea or bloating.
- Headaches or mood changes.
- Increased risk of blood clots or stroke (rare, but more common in smokers or those with pre-existing risk factors).
Application Site:
- Place the patch on clean, dry, and non-irritated skin (lower abdomen or buttocks, avoiding breasts).
- Rotate application sites to reduce skin irritation.
Timing: Follow your doctor’s instructions on how often to change the patch.
Avoid Water Interference: The patch is generally water-resistant, but prolonged exposure (like in a hot tub) may loosen it.
Who Should Not Use the Patch?
- People with a history of hormone-sensitive cancers (e.g., breast or uterine cancer), blood clots, stroke, or liver disease.
- Smokers over the age of 35 (due to increased clot risk).
