"Biest" refers to Biestrogens, which is a specific type of estrogen therapy that combines two types of estrogen—estriol and estradiol—in different ratios.
In a Biest 50/50 formulation, the ratio is 50% estriol and 50% estradiol. Here's a breakdown of these two forms of estrogen:
Estradiol: This is the most potent and commonly prescribed form of estrogen. It is the dominant estrogen in the body, particularly during the reproductive years. Estradiol is often used for HRT to treat symptoms of menopause, like hot flashes, vaginal dryness, and mood swings.
Estriol: This is a weaker form of estrogen that is considered "safer" in some respects because it is less likely to stimulate estrogen-sensitive tissues like the breast and endometrium (lining of the uterus). It is often used in bioidentical hormone replacement therapy (BHRT) due to its gentler action.
- Balanced estrogenic effects: The combination may provide a more balanced effect, reducing side effects that can come with higher doses of estradiol (e.g., breast tenderness, risk of blood clots).
- Customized therapy: Many women find this approach more suitable for their needs, especially if they are sensitive to synthetic estrogens or are seeking a more bioidentical solution.
- Potential benefits for vaginal health: Estriol, in particular, has been shown to help with vaginal dryness and other urogenital symptoms of menopause.
- As with any hormone therapy, there can be risks. These include headaches, weight gain, mood swings, and an increased risk of certain types of cancers (although estriol is considered less risky in this regard compared to estrone or estradiol).
- It's important to note that the safety and effectiveness of Biest 50/50 can vary from person to person, so it’s crucial to work closely with a healthcare provider to monitor treatment and adjust dosages as needed.